NEW YORK (CBSNewYork/AP) — U.S. stocks plunged in early trading Friday after Britons voted to leave the European Union.

The Dow Jones industrial average dropped 500 points, or 2.8 percent, to 17,515 in the first few minutes of trading.

MORE: Full Coverage From CBS News MoneyWatch

The Standard & Poor’s 500 index fell 57 points, or 2.7 percent, to 2,056x. The Nasdaq composite sank 158 points, or 3.2 percent, to 4,751.

It was the biggest drop for U.S. stocks since September.

“We’ll see how much of an impact it will make on the economy, the domestic economy here in the U.S.,” Yelena Shulyatyeva with Bloomberg Intelligence told CBS2’s Tony Aiello. “Right now, we don’t think it’s going to be a major impact.”

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